Cartilage Tissue Engineering Lab

February 9, 2010

Cartilage Tissue Engineering Lab at UCSD

Welcome to the UCSD CTE Lab
For the latest discoveries by the lab, see our publications.
Recent Events 11/1/2009 - NYC Marathon for Arthritis Foundation's Let Move Together Team Jennifer Antonacci, PhD Candidate, will be running the 2009 NYC Marathon on November 1 to raise $2,500 for the Arthritis Foundation's Let's Move Toget ...[more] 7/28/2009 - CTE Research Included in SDSC Genomics Workshop The CTE lab had a unique opportunity to connect with high school teachers from around the country. The teachers came from as far as Wisconsin to a Gen ...[more] 7/8/2009 - Press Conference with Lois Capps featuring Prof Steve Klisch Collaborating Professor Steve Klisch of Cal Poly was recently featured at the press conference of Lois Capps, Congresswoman for Santa Barbara and San ...[more] more news Recent Publications Watson D, Sage A, Chang AA, Schumacher BL, Sah RL: Growth of human septal chondrocytes in fibrin scaffolds. Am J Rhinol Allergy 24:19-22, 2010. [PubMed] Blewis ME, Lao BJ, Jadin KD, McCarty WJ, Bugbee WD, Firestein GS, Sah RL: Semi-permeable membrane retention of synovial fluid lubricants hyaluronan and proteoglycan 4 for a biomimetic bioreactor. Biotechnol Bioeng ePub:2009.12.15, 2010. [PubMed] McCarty WJ, Pallante AL, Rone RJ, Bugbee WD, Sah RL: The proteoglycan metabolism of articular cartilage in joint-scale culture. Tissue Eng Part A ePub:2010.01.13, 2010. PMCID:PMC Journal- In Process [PubMed] more publications
The Cartilage Tissue Engineering Laboratory in the Department of Bioengineering at the University of California, San Diego was formed in July, 1992 by Prof. Robert Sah. Principal Investigators of the CTE Lab are Prof. William Bugbee (Orthopaedic Surgery), Prof. Deborah Watson (Head and Neck Surgery), as well as the director of the lab, Prof. Robert Sah. We are members of the Institute of Engineering in Medicine and also the UCSD Stein Institute for Research on Aging.
In the CTE Lab, we study the *biological processes* of cartilage development & growth aging degeneration repair, regeneration, & replacement by examining the *relationships* between tissue metabolism composition biomechanics structure with the ultimate goal of *improving clinical* treatment diagnosis prevention.
Our studies are currently supported by grants from the following government agencies and foundations, including:
Howard Hughes Medical Institute National Institutes of Health National Science Foundation Veterans Administration Medical Center Veterans Affairs Research & Development
as well as contracts, grants, and gifts from various industries, including:
Arthrex Articular Engineering	BREG Synthasome
We collaborate with several groups at UCSD in the Department of Bioengineering within the Jacobs School of Engineering, as well as the Departments of Orthopaedics, Rheumatology, and Radiology within the School of Medicine. We also enjoy active collaborations with experts outside of UCSD, including Prof. Steve Klisch at California Polytechnic State University-San Luis Obispo. We welcome inquiries from interested individuals. Individuals with interest in doing research in the lab can inquire about research opportunities. PLEASE NOTE! Patients interested in clinical care are encouraged to contact the principal investigators who are practicing physicians. For joint replacement & arthritis surgery or cartilage restoration & transplantation, please contact the clinical office of William Bugbee, MD at Scripps Clinic, or the Department of Orthopaedic Surgery at UCSD. For facial plastic or facial reconstructive surgery, please contact Deborah Watson, MD, Co-director, Facial Plastic and Reconstructive Surgery at the UCSD Medical Center. UCSD Medical Center also offers specialty services in clinical orthopaedics in the areas of sports medicine, rehabilitation medicine and physical therapy.