Cartilage Tissue Engineering Lab at UCSD

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Publications
Publication listings with a link are available to individuals or organizations with subscriptions to the journal. Articles are in pdf format and require Acrobat Reader to view them.

List by Year: 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1991 1990 1989 1988
List by Topic: Aging & Osteoarthritis, Biochemistry & Metabolism, Focal Defects, Friction, Wear, Lubrication, Growth & Maturation, Mechanobiology, Osteochondral Allografts, PRG4/SZP/Lubricin, Repair, Review, Septal Cartilage Tissue Engineering, Tissue Engineering, Tissue Mechanics, Tissue Structure,
List by Personnel
2005 Robert Sah
Journal Papers
Albrecht DR, Liu Tsang V, Sah RL, Bhatia, SN: Photo- and electropatterning of hydrogel-encapsulated living cell arrays. Lab Chip 5:111-8, 2005. [PubMed] Allen T, Robertson CM, Pennock AT, Bugbee WD, Harwood FL, Wong VW, Chen AC, Sah RL, Amiel D: Analysis of stored osteochondral allografts at the time of surgical implantation. Am J Sports Med 33:1479-84, 2005. Chia SH, Homicz MR, Schumacher BL, Thonar EJ, Masuda K, Sah RL, Watson D: Characterization of human nasal septal chondrocytes cultured in alginate. J Am Coll Surg 200:691-704, 2005. Englert C, McGowan KB, Klein TJ, Giurea A, Schumacher BL, Sah RL: Inhibition of integrative cartilage repair by proteoglycan 4 in synovial fluid. Arthritis Rheum 52:1091-9, 2005. Hicks DL, Sage AB, Schumacher BL, Sah RL, Watson D: Growth and phenotype of low-density nasal septal chondrocyte monolayers. Otolaryngol Head Neck Surg 133:417-22, 2005. Jadin KD, Wong BL, Bae WC, Li KW, Williamson AK, Schumacher BL, Price JH, Sah RL: Depth-varying density and organization of chondrocyte in immature and mature bovine articular cartilage assessed by 3D imaging and analysis. J Histochem Cytochem 53:1109-19, 2005. Klisch SM, Sah RL, Hoger A: A cartilage growth mixture model for infinitesimal strains: solutions of boundary-value problems related to in vitro growth experiments. Biomech Model Mechanobiol 3:209-23, 2005. Lewis CW, Williamson AK, Chen AC, Bae WC, Temple MM, Wong VW, Nugent GE, James SP, Wheeler DL, Sah RL, Kawcak CE: Evaluation of subchondral bone mineral density associated with articular cartilage structure and integrity in normal equine joints with different functional demands. Am J Vet Res 66:1823-9, 2005. McGowan KB, Sah RL: Treatment of cartilage with beta-aminopropionitrile accelerates subsequent collagen maturation and modulates integrative repair. J Orthop Res 23:594-601, 2005. Miyamoto K, An HS, Sah RL, Akeda K, Okuma M, Otten L, Thonar EJ-MA, Masuda K: Exposure to pulsed low intensity ultrasound stimulates extracellular matrix metabolism of bovine intervertebral disc cells cultured in alginate beads. Spine 30:2398-405, 2005. Richmon JD, Sage AB, Shelton E, Schumacher BL, Sah RL, Watson D: Effect of growth factors on cell proliferation, matrix deposition, and morphology of human nasal septal chondrocytes cultured in monolayer. Laryngoscope 115:1553-60, 2005. Richmon JD, Sage AB, Wong VW, Chen AC, Pan C, Sah RL, Watson D: Tensile biomechanical properties of human nasal septal cartilage. Am J Rhinol 19:617-22, 2005. Schumacher BL, Schmidt TA, Voegtline MS, Chen AC, Sah RL: Proteoglycan 4 (PRG4) synthesis and immunolocalization in bovine meniscus. J Orthop Res 23:562-8, 2005. Williams GM, Klein TJ, Sah RL: Cell density alters matrix accumulation in two distinct fractions and the mechanical integrity of alginate-chondrocyte constructs. Acta Biomater 1:625-33, 2005.
Book Sections
Sah RL, Klein TJ, Schmidt TA, Albrecht DR, Bae WC, Nugent GE, McGowan KB, Temple MM, Jadin KD, Schumacher BL, Chen AC, Sandy JD: Articular cartilage repair, regeneration, and replacement. In: Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th Ed., ed by Koopman WJ, Moreland LW, Lippincott Williams & Wilkins, Philadelphia, 2005, pp 2277-301. [ISBN: 078174671X] Schmidt TA, Schumacher BL, Han EH, Klein TJ, Voegtline MS, Sah RL: Chemomechanical coupling in articular cartilage: IL-1alpha and TGF-beta1 regulate chondrocyte synthesis and secretion of proteoglycan 4. In: Physical Regulation of Skeletal Repair, ed by Aaron RK, Bolander ME, American Academy of Orthopaedic Surgeons, , 2005, pp 151-62. [ISBN: 0892033630]
Abstracts
Albrecht DR, Sah RL, Bhatia SN: In vitro modulation of chondrocyte organization. Trans Orthop Res Soc 30:255, 2005. Asanbaeva A, Masuda K, Thonar EJ-MA, Klisch SM, Sah RL: Regulation of immature cartilage growth by IGF-I, TGF-alpha 1, BMP-7, and PDGF-AB: role of metabolic balance between fixed charge and collagen network. Trans Orthop Res Soc 30:8, 2005. Blewis ME, Schumacher BL, Klein TJ, Schmidt TA, Voegtline MS, Sah RL: Microenvironment regulation of superficial zone phenotype of chondrocytes. Trans Orthop Res Soc 30:1, 2005. Borazjani BH, Chen AC, Bae WC, Nugent GE, Schumacher BL, Voegtline MS, Patil S, DLima DD, Firestein GS, Sah RL, Bugbee WD: Mechanisms and consequences of chondrocyte injury during impact loading and insertion of human osteochondral grafts. Trans Orthop Res Soc 30:351, 2005. Chawla K, Klein TJ, Schumacher BL, Jadin KD, Schmidt TA, Chen AC, Wong V, Nakagawa K, Thonar EJ-MA, Masuda K, Sah RL: Enhanced formation of stratified tissue-engineered porcine cartilage from chondrocyte subpopulations with bone morphogenetic protein-7 (BMP-7). Trans Orthop Res Soc 30:294, 2005. Chujo T, Akeda K, Miyamoto K, An HS, Thonar E, Sah RL, Lenz ME, Masuda K: The effect of pulsed low intensity ultrasound on matrix metabolism by bovine tendon cells cultured in alginate beads. Trans Orthop Res Soc 30:752, 2005. Lewis CW, Williamson AK, Chen AC, Bae WC, Temple MM, Wong VW, Nugent GE, Harmel JL, Walker JE, James SP, Wheeler DL, Sah RL, Kawcak CE: Relationship between functional demand, subchondral bone mineral density, and articular cartilage structural and integrity. Trans Orthop Res Soc 30:1550, 2005. McGowan KB, Harwood F, Amiel D, Sah RL: Modulation of cartilage crosslink formation with beta-aminopropionitrile. Trans Orthop Res Soc 30:1356, 2005. Nugent GE, Schmidt TA, Schumacher BL, Voegtline MS, Bae WC, Jadin KD, Sah RL: Biomechanical regulation of chondrocyte synthesis of PRG4. Trans Orthop Res Soc 30:81, 2005. Schmidt TA, Schumacher BL, Nugent GE, Gastelum NS, Sah RL: PRG4 contributes to a "sacrificial layer" mechanism of boundary lubrication of articular cartilage. Trans Orthop Res Soc 30:900, 2005. Wedig ML, Bae WC, Temple MM, Sah RL, Gray ML: [GAG] profiles in "normal" human articular cartilage. Trans Orthop Res Soc 30:358, 2005. Williams GM, Klein TJ, Sah RL: Interaction of secreted ECM determines the integrity of engineered cartilage. Trans Orthop Res Soc 30:1778, 2005.

2005 Robert Sah